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Channel: Skin Cancer Connection Blog » perineural invasion
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Squamous Cell Carcinoma Lower Lip

A man in his thirties with lifelong h/o severe actinic cheilitis of left lower lip. Recurrent flare-ups of cheilitis have been treated as recurrent herpetic infection. Recently he has experienced...

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Perineural Invasion

Perineural invasion is strongly indicative of aggressive behavior and risk of metastases. True perineural invasion requires histologic finding of cancer invasion of the nerve or cancer invasion of  the...

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Squamous Cell Carcinoma of lower lip – Subtotal Involvement

Thirty something year old with total lower lip reconstruction following excision of Squamous Cell carcinoma (SCCa) lower lip Mohs. Perineural invasion was seen on a shave biopsy. Mohs identified cancer...

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Perineural Invasion

Perineural invasion (PI) in skin cancers is a significant finding potentially requiring additional treatment. There are four levels of PI: perineural inflammation, minimal microscopic invasion of small...

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High Risk Squamous Cell Carcinomas of the Face

The vast majority of cutaneous squamous cell carcinomas (SCC) have only a limited local impact on the area of involvement. However, some of these SCC’s have an increased risk of recurrence, regional...

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